Reversing the Risk Factor Paradox: Is Daily Nocturnal Hemodialysis the Solution?
In this review we summarize the growing body of evidence suggesting that daily nocturnal hemodialysis (NHD), a novel...
Below is a collection of news and related articles to aid you in your decision regarding home hemodialysis with Home Dialysis Centers.
In this review we summarize the growing body of evidence suggesting that daily nocturnal hemodialysis (NHD), a novel...
Nocturnal HD represents a promising, viable, alternative renal replacement therapy for patients experiencing PD failure...
Enhanced uraemia control by NHD improved both exercise duration and capacity. When coupled with augmented uraemia...
Home hemodialysis has been a therapeutic option for almost 4 decades. The complexity of dialysis equipment has been a factor-limiting adoption of this modality. We performed a feasibility study to demonstrate the safety...
This preliminary study revealed that, compared with conventional hemodialysis (3 times weekly), frequent nocturnal hemodialysis improved left ventricular mass...
Hyperphosphatemia is an almost universal finding in patients with end-stage renal disease and is associated with increased all-cause mortality, cardiovascular mortality, and vascular calcification. These associations have raised the question of whether reducing phosphorus levels could result in...
A recent resurgence of interest in home dialysis treatment is being driven by several factors, including (1) improved clinical outcomes associated with more frequent hemodialysis possible with home therapy...
The impact of a higher dose of dialysis on patient mortality and morbidity has been studied in several randomized clinical trials, including the National Cooperative Dialysis Trial and the HEMO study. The latter trial, conducted from 1995 to 2002 and the largest conducted to date in long-term hemodialysis patients, was designed to determine if a higher dose of dialysis, as provided by a 3-times-per-week schedule, or the use of high-flux dialyzers decreased mortality and morbidity in long-term hemodialysis patients. Those patients randomized to...
Use of ultrapure dialysate (bacteria < 0.1 CFU/mL and endotoxin < 0.03 EU/mL) is associated with a reduction in inflammation and morbidity in patients treated with conventional thrice-weekly dialysis. The improved outcomes obtained with more frequent dialysis schedules have reawakened interest in home hemodialysis. More frequent dialysis also appears to reduce inflammation, and whether combining more frequent dialysis with use of ultrapure dialysate will have an additive effect on inflammation and...
The hemoglobin (Hb) and the serum albumin (S.Alb) concentration commonly rise during seated, conventional thrice-weekly 4 to 4.5 hr hemodialysis (CHD) as a result of rapid fluid removal from the intravascular compartment. Conversely, in long, slow, recumbent nocturnal home hemodialysis (NHHD), the intra-dialytic S.Alb concentration has been ...
In recent years, there has been an increased interest in performing hemodialysis (HD) more frequently than thrice weekly, particularly in the home setting. This interest has been stimulated by some studies that have indicated significant benefits to performing more frequent HD on various medical and quality of life outcome measures. However, only...
The beneficial effects of daily hemodialysis on clinical outcomes have been widely reported. Such effects include improved control of blood pressure (usually with reduced doses of antihypertensive drugs) and of anemia (despite a reduction in erythropoietin dose),1 leading to improved quality of life.2 Among these beneficial effects, the impact of daily hemodialysis on nutritional state2 should not be overlooked. In the...
Aim: To identify the major difficulties nephrologists in the US face in providing adequate dialysis. Methods: To identify the perceived obstacles to achieving adequate dialysis in the US, 30 clinical support specialists responsible for nursing education and training were polled...
More frequent hemodialysis (5 or more times weekly, both short during the day and long overnight) has been shown to improve patient well-being, reduce symptoms during and between treatments, and have beneficial effects on clinical outcomes. Because of the relatively small...
Purpose of review: The HEMO study results have shown that increasing dialysis dose in conventional thrice weekly hemodialysis does not improve patient outcomes. Interest has therefore turned to more frequent (daily) hemodialysis treatments. This review covers the rationale for such an approach together with a current review...
Background. Concerns about vascular access failure may have limited the widespread use of daily haemodialysis (DHD). We assessed the incidence and type of vascular access complications...
The London Daily/Nocturnal Hemodialysis Study, a prospective, comparative, nonrandomized study, directly compared outcomes of quotidian (daily) hemodialysis patients with conventional thrice-weekly hemodialysis patients. Patients were assigned to either daily (short-hours) hemodialysis (n = 11) or nocturnal hemodialysis...
Thrice-weekly hemodialysis is the most commonly used form of renal replacement therapy, yet it is associated with unacceptably high morbidity and mortality. Attempts to improve outcomes for hemodialysis patients by increasing their per-session dose of dialysis have recently proven unsatisfactory in the multicentered...
Cardiovascular disease remains the leading cause of morbidity and mortality for patients with end-stage renal disease (ESRD). Frequent intensive hemodialysis (short daily hemodialysis [2 hours per session, six sessions per week] and...
Purpose: Several studies have showed that nocturnal home hemodialysis (NHD, 6 times weekly 6–8 h) results in a better outcome. How do patients...
Hyperphosphatemia and poor uremia control are established cardiovascular risk factors in patients with end-stage renal disease (ESRD) associated with impaired endothelial dependent and independent vasodilation (EDV and EIV). Nocturnal hemodialysis [6 × 8 h/week] augments dialysis dose and offers normal phosphate (Pi) balance...
More frequent dialysis is thought to be associated with increased heparin requirements; however, limited data are available which compare heparin requirements of conventional to daily dialysis...
Background: Daily hemodialysis (DHD) markedly ameliorates cardiovascular instability (CVI) and discomfort (DIS) during dialysis, but patients continue to have some of these problems during DHD. We studied what contributed to these problems during 4445...
Frequent dialyses are sometimes perceived as increasing the risk of blood access malfunction and decreased longevity. This review of the literature...
ABSTRACT. Interest in quotidian (daily) hemodialysis (HD) is growing. Some advocate short-hours high-efficiency daily HD (SDH) and others long-hours slow-flow nocturnal HD (NH) while the patient is asleep, both being used 5 to 7 d/week. The London Daily/Nocturnal Hemodialysis Study was the first attempt to obtain data of SDH and NH that may be compared with conventional thrice weekly HD (CH). This was a 4-yr observational study designed to enter and follow 40 patients...
Objective: Nutritional status is an important predictor of outcome in dialysis patients. Long nocturnal dialysis (LND) improves clearances, and potentially can have a beneficial...
Background. Nocturnal home hemodialysis (NHD, 6–7 times weekly 6–8 hours) is a promising dialysis modality. On-line distant monitoring is complicated and expensive, and its usefulness should be evaluated. Methods. Since December 2001, 15 patients were included in a Dutch NHD project ('Nocturne'). So far, 3 patients received...
Nocturnal hemodialysis (NHD)[8 hrs, 6/week] is a novel renal replacement therapy that lowers daytime blood pressure and plasma norepinephrine and corrects uremic related sleep apnea. Our aim was to test the hypothesis that NHD would...
Objective: Long nocturnal dialysis (LND) has been advocated as a way to improve dialysis outcomes by improving adequacy. The effect of long dialysis on calcium phosphorus balance and bone mineralism has not been studied. On one hand...
A program of home hemodialysis (HHD) was instituted at a University Hospital in 1998. In this study we evaluated experiences in training patients for HHD with and without an assistant...
Background: End-stage renal disease (ESRD) patients undergoing conventional in-center hemodialysis (CHD)[3 sessions per week, 4 hours/session] have poor productivity which often results in unemployment. Nocturnal hemodialysis...
Background: Home hemodialysis is usually considered a superior therapy, whose decline is related to demographic, social, psychological and financial factors as well as to competition with renal transplantation and PD. Methods: A home hemodialysis program was started in November...
Background. Advanced glycation end-products (AGEs) accumulate in uraemia, regardless of hyperglycaemic conditions, and may contribute to the onset of some long-term complications, such as atherosclerosis, amyloidosis, and neurodegenerative processes. In this study...
